Hamas leader: Cease-fire with Israel near

JERUSALEM (AP) — A diplomatic push to end Israel's nearly weeklong offensive in the Gaza Strip gained momentum Tuesday, with Egypt's president predicting that airstrikes would end within hours and Israel's prime minister saying his country would be a "willing partner" to a cease-fire with the Islamic militant group Hamas.

As international diplomats raced across the region to cement a deal, a senior Hamas official said an agreement was close even as relentless airstrikes and rocket attacks between the two sides continued. President Barack Obama dispatched Secretary of State Hillary Rodham Clinton to the Mideast from Cambodia, where she had accompanied him on a visit.

"We haven't struck the deal yet, but we are progressing and it will most likely be tonight," Moussa Abu Marzouk said Tuesday from Cairo, where cease-fire talks were being held.

Egyptian President Mohammed Morsi, perhaps the most important interlocutor between Hamas, which rules the Palestinian territory, and the Israelis, said the negotiations between the two sides will yield "positive results" during the coming hours.

In Brussels, a senior official of the European Union's foreign service said a cease-fire would include an end of Israeli airstrikes and targeted killings in Gaza, the opening of Gaza crossing points and an end to rocket attacks on Israel. The official spoke on condition of anonymity because he was not authorized to speak to the media.

Violence raged on as the talks continued. An airstrike late Tuesday killed two journalists who work for the Hamas TV station, Al-Aqsa, according to a statement from the channel. The men were in a car hit by an airstrike, Gaza health official Ashraf al-Kidra said. Israel claims that many Hamas journalists are involved in militant activities. Earlier this week it targeted the station's offices, saying it served as a Hamas communications post.

By Tuesday, 128 Palestinians, including at least 54 civilians, were killed since Israel began an air onslaught that has so far included nearly 1,500 strikes. Some 840 people have been wounded, including 225 children, Gaza health officials said.

Three Israeli civilians have also been killed and dozens wounded since the fighting began last week, the numbers possibly kept down by a rocket-defense system that Israel developed with U.S. funding. More than 1,000 rockets have been fired at Israel this week, the military said.

Late Tuesday, a Palestinian rocket hit a house in the central Israeli city of Rishon Letzion, wounding two people and badly damaging the top two floors of the building, police spokesman Micky Rosenfeld said.

With the death toll rising, the international community stepped up efforts to bring a halt to the fighting that began last Wednesday with an Israel's assassination of the Hamas military chief.

"If a long-term solution can be put in place through diplomatic means, then Israel would be a willing partner to such a solution. But if stronger military action proves necessary to stop the constant barrage of rockets, Israel wouldn't hesitate to do what is necessary to defend our people," Israeli Prime Minister Benjamin Netanyahu said during a joint press conference in Jerusalem with visiting U.N. chief Ban Ki-moon.

Ban condemned Palestinian rocket attacks, but urged Israel to show "maximum restraint."

"Further escalation benefits no one," he said.

Minutes before Ban's arrival in Jerusalem from Egypt, Palestinian militants fired a rocket toward the holy city. Earlier Tuesday, a man identified as Hamas' militant commander urged his fighters to keep up attacks on Israel, even as Israeli airstrikes killed a senior Hamas militant identified as Amin al-Dada and five others in a separate attack on a car, according to Gaza health officials.

Israeli warplanes dropped leaflets on several Gaza neighborhoods asking residents to evacuate and head toward the center of Gaza City along specific roads. The army "is not targeting any of you, and doesn't want to harm you or your families," the leaflets said. Palestinian militants urged residents to ignore the warnings, calling them "psychological warfare."

Clinton was scheduled to meet with Netanyahu in Jerusalem, Palestinian President Mahmoud Abbas in the West Bank and Egyptian leaders in Cairo. Turkey's foreign minister and a delegation of Arab League foreign ministers traveled to Gaza on a separate truce mission. Airstrikes continued to hit Gaza even as they entered the territory.

"Turkey is standing by you," Turkish Foreign Minister Ahmet Davutoglu told the Hamas prime minister in Gaza, Ismail Haniyeh. "Our demand is clear. Israel should end its aggression immediately and lift the inhumane blockade imposed on Gaza."

It was unclear how diplomatic efforts to achieve a cease-fire and stave off a threatened Israeli ground invasion into Gaza were hampered by the hard-to-bridge positions staked out by both sides — and by the persistent attacks. Tens of thousands of Israeli soldiers have been dispatched to the Gaza border in case of a decision to invade.

Residents of Jerusalem ran for cover Tuesday as sirens sounded after Palestinians fired a rocket toward the holy city for the second time since the fighting started last Wednesday.

Rosenfeld said the rocket landed harmlessly in an open area in Gush Etzion, a collection of Jewish West Bank settlements southeast of the city. Last Friday's attempt to hit Jerusalem, nearly 80 kilometers (50 miles) from Gaza, landed in the same area. No one was wounded in either attack.

Jerusalem had previously been considered beyond the range of Gaza rockets — and an unlikely target because it is home to the Al-Aqsa Mosque compound, Islam's third-holiest shrine.

In a sign of the difficulty diplomats will have in forging such a cease-fire, a man identified as Mohammed Deif, Hamas' elusive military commander, urged his fighters to keep up attacks on Israel.

Speaking from hiding on Hamas-run TV and radio, Deif said Hamas "must invest all resources to uproot this aggressor from our land," a reference to Israel.

Deif is one of the founders of Hamas' military wing and was its top commander until he was seriously wounded in an Israeli airstrike in 2003. He was replaced as the de facto leader by Ahmed Jabari, who was assassinated by Israel last week in the opening salvo of its latest Gaza offensive.

The U.S. considers Hamas, which has killed hundreds of Israelis in suicide and other attacks, to be a terror group and does not meet with its officials. The Obama administration blames Hamas for the latest eruption of violence and says Israel has the right to defend itself. At the same time, it has warned against a ground invasion, saying it could send casualties spiraling.

Netanyahu said earlier Tuesday that Israel was exploring a diplomatic solution, but wouldn't balk at a broader military operation.

"I prefer a diplomatic solution," Netanyahu said in a statement after meeting with Germany's Foreign Minister Guido Westerwelle, who is also in the region trying to advance peace efforts. "But if the fire continues, we will be forced to take broader measures and will not hesitate to do so."

Westerwelle said a truce must be urgently pursued, "but of course, there is one precondition for everything else, and this is a stop of the missile attacks against Israel."

The conflict erupted last week, when a resurgence in rocket fire from Gaza set off the Israeli offensive, which included hundreds of airstrikes on militants' underground rocket launchers and weapons' stores.

The onslaught turned deadlier over the weekend, as airstrikes began targeting the homes of suspected Hamas activists, leading to a spike in civilian casualties. Israel sent warnings in some cases, witnesses said, but in other instances missiles hit suddenly, burying residents under the rubble of their homes.

Hamas is deeply rooted in densely populated Gaza, and the movement's activists live in the midst of ordinary Gazans. Israel says militants are using civilians as human shields, both for their own safety and to launch rocket strikes from residential neighborhoods.

Early Tuesday, Israeli aircraft targeted another Hamas symbol of power, the headquarters of the bank senior Hamas officials set up to sidestep international sanctions on the militant group's rule. The inside of the bank was destroyed. A building supply business in the basement was damaged.

Fuad Hijazi and two of his toddler sons were killed Monday evening when missiles struck their one-story shack in northern Gaza, leaving a crater about two to three meters (seven to 10 feet) deep in the densely populated neighborhood. Residents said the father was not a militant.

The conflict showed signs of spilling into the West Bank, as hundreds of Palestinian protesters in the town of Jenin clashed with Israeli forces during a demonstration against Israel's Gaza offensive.

Two Palestinian protesters were killed in anti-Israel demonstrations in the West Bank on Monday, according to Palestinian officials. Separate clashes occurred Tuesday in Ramallah, the seat of the Palestinian government, during the funeral for one of the dead.

Palestinian President Mahmoud Abbas, who lost control of Gaza to Hamas in 2007, now governs from the West Bank. Abbas claims to represent both areas, and there is widespread sympathy among West Bank Palestinians for their brethren in Gaza.

Israel demands an end to rocket fire from Gaza and a halt to weapons smuggling into Gaza through tunnels under the border with Egypt. It also wants international guarantees that Hamas will not rearm or use Egypt's Sinai region, which abuts both Gaza and southern Israel, to attack Israelis.

Hamas wants Israel to halt all attacks on Gaza and lift tight restrictions on trade and movement in and out of the territory that have been in place since Hamas seized Gaza by force in 2007. Israel has rejected such demands in the past.

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Associated Press writers Hamza Hendawi in Cairo, and Karin Laub and Ibrahim Barzak in Gaza City, Gaza Strip, contributed to this report.

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Myanmar or Burma? Obama calls it both on visit

YANGON, Myanmar (AP) — Officially at least, America still calls this Southeast Asian nation Burma, the favored appellation of dissidents and pro-democracy activists who opposed the former military junta's move to summarily change its name 23 years ago.

President Barack Obama used that name during his historic visit Monday, but he also called Burma what its government and many other people have been calling it for years: Myanmar.

Obama's use of that single word was warmly welcomed by top government officials here, who immediately imbued it with significance.

Myanmar presidential adviser Ko Ko Hlaing called the wording "very positive" and said it was an "acknowledgement of Myanmar's government," which has taken major steps toward easing repression and transitioning to democratic rule since the military stepped aside last year.

Speaking aboard Air Force One after Obama's departure, U.S. Deputy National Security Adviser Ben Rhodes said the presidential phrasing was "a diplomatic courtesy" for Myanmar's reformist President Thein Sein.

"It doesn't change the fact that the United States government position is still Burma," he said. "But we've said we recognize that different people call this country by different names. Our view is that is something we can continue to discuss."

The issue is so sensitive that Obama's aides had said earlier Monday he would likely avoid mentioning either politically charged name. But he used both during his six-hour trip — "Myanmar" during morning talks with Thein Sein, "Burma" afterward while visiting with opposition leader Aung San Suu Kyi.

Suu Kyi herself was criticized by the government for calling the nation Burma during a trip to Europe over the summer. The government said she should use the proper name, "Republic of the Union of Myanmar," as stated in the constitution. But Suu Kyi has said "it's for each individual to make his or her own choice as to which he or she uses."

The debate is almost exclusively confined to the English language.

Myanmar, comprising a vast array of ethnic groups, did not exist as a single entity until it was colonized by the British in the 19th century. The country achieved independence in 1948 and took the English-language name used by its former rulers, Burma.

But it was formally known in Burmese, the national language, as "myanma naing ngan" or more colloquially as "bama pyi" or "country of Burma." Both those usages persist, and the national anthem still refers to "bama pyi."

When the now-defunct army junta altered the name in 1989, the change applied only to the English-language title.

But exiles and critics, just like the U.S., kept on using "Burma." And some, including the U.S., still call its main city "Rangoon" instead of Yangon.

But like Myanmar itself, that has all begun to change.

Visiting U.S. senators have used both names. Even at congressional hearings in Washington, there's an occasional mention of "Myanmar."

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Associated Press writer Julie Pace contributed to this report from Air Force One. Pitman reported from Bangkok.

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Justin Bieber gets love at American Music Awards

Justin Bieber may be Canadian, but he was the all-American boy at Sunday night's American Music Awards.

The pop singer dominated the awards show, winning three trophies, including artist of the year. His mom joined him onstage as he collected the award, beating out Rihanna, Maroon 5, Katy Perry and Drake.

"I wanted to thank you for always believing in me," Bieber said, looking to his mom.

The 18-year-old also won the honor in 2010. He said it's "hard growing up with everyone watching me" and asked that people continue to believe in him.

But the teenager who brought his mom as a date also got in some grinding with Nicki Minaj — who shared the stage with him and took home two awards — and a kiss on the neck from presenter Jenny McCarthy.

"Wow. I feel violated right now," he said, laughing.

"I did grab his butt," McCarthy said backstage. "I couldn't help it. He was just so delicious. So little. I wanted to tear his head off and eat it."

Another collaboration was the night's most colorful performance: Korean rapper PSY and MC Hammer. Hammer joined the buzzed-about pop star for his viral hit "Gangnam Style." PSY rocked traditional "Hammer" pants as they danced to his jam and to Hammer's "Too Legit to Quit."

Minaj, who wore three different wigs and four outfits throughout the night, repeated her AMAs wins from last year, picking up trophies for favorite rap/hip-hop artist and album for "Pink Friday: Roman Reloaded." She was in an all-white get-up, including fur coat and pink hair when she performed her new song "Freedom." The scene was ghostly and snowy, as a choir — also in white — joined her onstage. One background singer stole the performance, belting semi-high notes as Minaj looked on.

Usher kicked off the three-hour ABC-televised show with green laser lights beaming onstage as he performed a medley of songs, including "Numb," ''Climax" and "Can't Stop, Won't Stop," which featured a smoky floor and a number of backup dancers, as Usher jammed in all black, with the exception of his red shoes. He won favorite soul/R&B male artist.

His protege Bieber won favorite pop/rock male artist in the first award handed out and gave a shout-out to those who didn't think he would last on the music scene.

"I want to say this is for all the haters who thought I was just here for one or two years. I feel like I'm going to be here for a very long time," he said.

He also won favorite pop/rock album for his platinum-selling third album, "Believe." He gave a stripped down, acoustic performance of "As Long As You Love Me," then transitioned to the dance-heavy "Beauty and a Beat," where Minaj joined him onstage, grinding with the teen for a few seconds.

Swift won her fifth consecutive award for favorite country female artist.

"This is unreal. I want to thank the fans. You guys are the ones who voted on this," she said.

Swift gave a masquerade-themed performance of the pop song "I Knew You Were Trouble." She sang onstage in a light dress while dancers wore mostly black. But then she changed into a red corset and black skirt, matching their dark mood. She even danced and sang on the floor as lights flickered throughout the performance.

Dick Clark, who created the AMAs, was remembered by Ryan Seacrest and an upbeat performance by Stevie Wonder.

"What a producer he was," said Seacrest, as Wonder sang his hits, including "My Cherie Amour."

Carly Rae Jepsen, who performed early in the night, won favorite new artist.

"I am floored. Wow," she said, thanking Bieber and his manager, Scooter Braun.

Party girl Ke$ha was glammed up on the red carpet, rocking long, flowy blonde hair and a light pink dress. She switched to her normal attire when she performed her hit single "Die Young." It was tribal, with shirtless dancers in skin-tight pants, silver hair and skeleton-painted faces, who also played the drums. Ke$ha was pants-less, rocking knee-high boots and rolling on the floor as she finished up the song.

Minaj and Christina Aguilera were blonde bombshells, too: Minaj's hair was busy and full of volume and she sported a neon strapless gown to accept her first award. Aguilera wore a blonde bob in a purple dress that matched her eyeshadow.

Aguilera performed a medley of material from her new album and joined Pitbull onstage.

Kelly Clarkson also hit the stage, making a nod to her "American Idol" roots with a number on her dress and three judges looking on as she sang "Miss Independent." Then she went into "Since U Been Gone," ''Stronger" and "Catch My Breath."

Fellow "Idol" winner Carrie Underwood won best favorite country album and performed, hitting the right notes while singing "Two Black Cadillacs." She talked about singing competition shows backstage.

"These people that go on these shows are so talented, you know? And I would love to see if so many of the other artists that are out there today would go back and try out for these shows, because they might get their behinds kicked by some of the contestants," she said.

Luke Bryan won favorite country male artist and Lady Antebellum favorite country group.

American Music Awards nominees were selected based on sales and airplay, and fans chose the winners by voting online. At this award show, even the stars were fans: Pink said on the red carpet that she'd like to collaborate with Lauryn Hill. Cyndi Lauper said her musical playlist includes Pink and Minaj. Boy band The Wanted said they were excited to see PSY and Colbie Caillat wanted to watch No Doubt.

"What makes the American Music Awards special is the fans choose the winning artists," said Chester Bennington of Linkin Park, who won favorite alternative rock artist and performed "Burn It Down," as Brandy sang along and Gwen Stefani, Usher and Phillip Phillips bobbed their heads.

David Guetta won the show's first-ever electronic dance music award. Non-televised awards went to Katy Perry for pop/rock female artist, Beyonce for soul/R&B female artist, Adele for adult contemporary artist and Shakira for Latin artist.

Along with Rihanna, Minaj was the top nominee with four nominations.

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ABC is owned by The Walt Disney Co.

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AP Entertainment Writer Sandy Cohen contributed to this report from Los Angeles.

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Follow Mesfin Fekadu on Twitter at http://twitter.com/MusicMesfin

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Palestinian death toll in Gaza reaches 100: Health Ministry

GAZA (Reuters) - The number of Palestinians killed in Gaza during Israel's on-going offensive reached 100 on Monday, the Hamas-run Health Ministry said.

On his Facebook page, ministry spokesman Ashraf Al-Qidra listed Mohammed Tbail, killed in an air strike in Nusseirat refugee camp, as the 100th Palestinian fatality.

Qidra said the Palestinian dead included 24 children and 10 women. Ministry figures for the number of men killed in the conflict with Israel make no distinction between civilians and militants.

According to the ministry, 850 people have been wounded in Gaza since the hostilities began on Wednesday. They included 260 children and 140 women.

Israel puts its death toll since Wednesday at three civilians - two men and a woman killed by a rocket fired from Gaza. Police said more than 60 people have been wounded.

(Reporting by Nidal al-Mughrabi, Writing by Jeffrey Heller in Jerusalem, Editing by Allyn Fisher-Ilan)

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Obama warns against 'ramping up' in Gaza crisis

BANGKOK (AP) — President Barack Obama said Sunday an incursion by Israel's forces into the Gaza Strip could only deepen its death toll, cautioning against an escalation even as he defended the Jewish state's right to defend itself. Obama also warned Palestinians the crisis could crush peace hopes for years.

"Israel has every right to expect that it does not have missiles fired into its territory," Obama said at the start of a three-nation tour in Asia.

"If that can be accomplished without a ramping up of military activity in Gaza, that's preferable," he said. "It's not just preferable for the people of Gaza. It's also preferable for Israelis, because if Israeli troops are in Gaza, they're much more at risk of incurring fatalities or being wounded."

Obama's comments came as Israel's campaign against Hamas militants in Gaza blasted into its fifth day. Israel is at a crossroads of whether to launch a ground invasion or pursue Egyptian-led truce efforts. Obama sought to defend the U.S. ally's rights while pushing for a halt in the violence.

Obama made his remarks during a news conference at the start of a four-day trip, a visit designed to expand the U.S. economic and military footprint in a region long dominated by China.

But the developments in and around Israel illustrated the foreign policy challenges facing Obama. Even as he mounted a proactive mission in Southeast Asia, he was forced into a reactive mode to respond to conflict in the Middle East that he has been unable to help resolve.

From Thailand, Obama also defended his decision to go to Myanmar, also known as Burma, as some critics called his presence premature.

Obama will be the first U.S. president to visit the country, which is moving from a brutal reign toward democracy but still holds political prisoners and is living with ethnic violence.

"This is not an endorsement of the Burmese government," Obama said. "This is an acknowledgement that there is a process underway inside that country that even a year and a half, two years ago, nobody foresaw."

Obama said he was also guided by Myanmar's longtime democracy advocate, Aung Sung Suu Kyi, who visited him recently at the White House.

"I'm not somebody who thinks the United States should stand on the sidelines and not get its hands dirty when there's an opportunity for us to encourage the better impulses inside a country," he said.

Change in a country can happen quickly, Obama said, if people believe "their voices are heard."

The president will also visit Cambodia during his Asia trip, which began Sunday in Thailand. He was here as a sign of U.S. commitment to a region his administration deems vital to U.S. economic growth, but the shadows of another Mideast conflict hung over his journey.

Israeli Prime Minister Benjamin Netanyahu declared Sunday that Israel was prepared to significantly expand its military operation in Gaza. Obama has been lobbying Netanyahu along with the leaders of Egypt and Turkey to try to halt the crisis — including stopping rocket strikes on Israel.

He said Israel was justly responding to "an ever escalating number of missiles that were landing not just in Israeli territory, but in areas that are populated. And there's no country on earth that would tolerate missiles raining down on its citizens from outside its borders."

Obama said Palestinians will have no chance to pursue their own state and a lasting peace with Israel as long as rockets are fired into Israel. He said he hoped for a clearer process over the next 48 hours — showing how much the Mideast conflict had intruded on his diplomatic mission to Asia.

Still, Obama got a red-carpet welcome, a dose of sightseeing and an official dinner of authentic Thai food.

In a news conference with Prime Minister Yingluck Shinawatra, both leaders spoke of deepening ties of trade, security and democracy. Obama's praised Thailand for being a supporter of democracy in Myanmar, the once-pariah state that is rapidly reforming. He said he appreciated the Thai prime minister's insights into Myanmar during their private meeting Sunday.

On a steamy day, Obama began with a visit to the Wat Pho Royal Monastery, a cultural must-see in Bangkok. In stocking feet, the president and U.S. Secretary of State Hillary Rodham Clinton walked up to a giant statue of Reclining Buddha, nearly 50 yards long and 45 feet high. The complex is a sprawling display of temples with colorful spires, gardens and waterfalls.

After his time at the temple, Obama paid a courtesy call to the ailing, 84-year-old U.S.-born King Bhumibol Adulyadej in his hospital quarters. The king, the longest serving living monarch, was born in Cambridge, Mass., and studied in Europe.

The centerpiece of the Asia trip comes Monday when Obama travels to Myanmar.

Obama aides see Myanmar as not only a success story but also as a signal to other countries that the U.S. will reward democratic behavior.

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Summary: A look at the 4 new Kindle Fire models

Amazon.com Inc. started shipping a large-screen version of its Kindle Fire tablet computer on Thursday, ahead of schedule. Here is a look at the new Fires announced in September:

— Kindle Fire, with 7-inch screen, 1024 by 600 pixels. $ 159, with 8 gigabytes of storage. Weighs 14.1 ounces. Battery life of 8.5 hours. Started shipping Sept. 14.

— Kindle Fire HD, with 7-inch screen, 1280 by 800 pixels. $ 199 with 16 GB of storage or $ 249 with 32 GB of storage. Weighs 13.9 ounces. Battery life of 11 hours. Started shipping Sept. 14.

— Kindle Fire HD 8.9″, with 8.9-inch screen, 1920 by 1200 pixels. $ 299 with 16 GB of storage or $ 369 with 32 GB of storage. Weighs 20 ounces. Battery life of 10 hours. Started shipping Thursday.

— Kindle Fire HD 8.9″ 4G LTE Wireless, with 8.9-inch screen, 1920 by 1200 pixels. $ 499 with 32 GB of storage or $ 599 with 64 GB of storage. Can connect to AT&T Inc.‘s 4G LTE wireless network. Weighs 20 ounces. Battery life of 10 hours. Will start shipping Tuesday.

Gadgets News Headlines – Yahoo! News

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'Twilight' finale dawns with $141.3M weekend

LOS ANGELES (AP) — The sun has set on the "Twilight" franchise with one last blockbuster opening for the supernatural romance.

"The Twilight Saga: Breaking Dawn — Part 2" sucked up $141.3 million domestically over opening weekend and $199.6 million more overseas for a worldwide debut of $340.9 million, according to studio estimates Sunday.

The finale ranks eighth on the list of all-time domestic debuts, and leaves "Twilight" with three of the top-10 openings, joining 2009's "New Moon" (No. 7 with $142.8 million) and last year's "Breaking Dawn — Part 1" (No. 9 with $138.1 million).

Last May's "The Avengers" is No. 1 with $207.4 million. "Batman" is the only other franchise with more than one top-10 opening: July's "The Dark Knight Rises" (No. 3 with $160.9 million) and 2008's "The Dark Knight" (No. 4 with $158.4 million).

Though "Twilight" still is a female-driven franchise, with girls and women making up 79 percent of the opening-weekend audience, the finale drew the series' biggest male crowds. Action-minded guys had more to root for in the finale as Kristen Stewart, Robert Pattinson and Taylor Lautner join in a colossal battle to end the story of warring vampires and werewolves.

"Our male audience particularly has enjoyed this film," said Richie Fay, head of distribution for Lionsgate, whose Summit Entertainment banner releases the "Twilight" movies. "With the action scenes in this one, we're hoping the holdover business will reflect the fact that males have kind of found it out."

The movie also helped lift Lionsgate into the big leagues among Hollywood studios. Paced by its $400 million smash with "The Hunger Games" and now the "Twilight" finale, Lionsgate surpassed $1 billion at the domestic box office for the first time.

Some box-office watchers had expected the last "Twilight" movie to open with a franchise record the way the "Harry Potter" finale did last year with $169.2 million, the second-best domestic debut on the charts.

"I thought that for the final installment, it might eclipse the franchise record, but to look at $141.3 million and say that's a disappointment, that's kind of crazy," said Paul Dergarabedian, an analyst for box-office tracker Hollywood.com. "It's one of the most consistently performing franchises of all time."

The "Twilight" finale took over the No. 1 spot from Sony's James Bond adventure "Skyfall," which slipped to second place with $41.5 million domestically in its second weekend. "Skyfall" raised its domestic total to $161.3 million.

The franchise's third film starring Daniel Craig as Bond, "Skyfall" began rolling out overseas in late October and has hit $507.9 million internationally at the box office. The film's global total climbed to $669.2 million, helping to lift Sony to its best year ever with $4 billion worldwide, topping the studio's $3.6 billion haul in 2009.

"Skyfall" passed the previous franchise high of $599.2 million worldwide for 2006's "Casino Royale."

Steven Spielberg and Daniel Day-Lewis' Civil War drama "Lincoln" expanded nationwide after a week in limited release and came in at No. 3 with $21 million. Distributed by Disney, "Lincoln" lifted its domestic haul to $22.4 million.

The comic drama "Silver Linings Playbook," released by the Weinstein Co., got off to a good start in limited release, taking in $458,430 in 16 theaters for a solid average of $28,652 a cinema. By comparison, the "Twilight" finale averaged $34,717 in 4,070 theaters.

"Silver Linings Playbook" stars Bradley Cooper, Jennifer Lawrence and Robert De Niro in a quirky romance involving a man fresh out of a psychiatric hospital and an emotionally troubled young widow.

Keira Knightley's period drama "Anna Karenina" also started well in limited release with $315,395 in 16 theaters, for an average of $19,712. The Focus Features film stars Knightley in the title role of Leo Tolstoy's tragic romance.

Estimated ticket sales for Friday through Sunday at U.S. and Canadian theaters, according to Hollywood.com. Where available, latest international numbers also are included. Final domestic figures will be released Monday.

1. "The Twilight Saga: Breaking Dawn — Part 2," $141.3 million ($199.6 million international).

2. "Skyfall," $41.5 million ($49.6 million international).

3. "Lincoln," $21 million.

4. "Wreck-It Ralph," $18.3 million ($4.8 million international).

5. "Flight," $8.6 million ($1 million international).

6. "Argo," $4.1 million.

7. "Taken 2," $2.1 million ($2 million international).

8. "Pitch Perfect," $1.3 million ($4.1 million international).

9. "Here Comes the Boom," $1.2 million.

10 (tie). "Cloud Atlas," $900,000.

10 (tie). "Hotel Transylvania," $900,000.

10 (tie). "The Sessions," $900,000.

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Online:

http://www.hollywood.com

http://www.rentrak.com

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Universal and Focus are owned by NBC Universal, a unit of Comcast Corp.; Sony, Columbia, Sony Screen Gems and Sony Pictures Classics are units of Sony Corp.; Paramount is owned by Viacom Inc.; Disney, Pixar and Marvel are owned by The Walt Disney Co.; Miramax is owned by Filmyard Holdings LLC; 20th Century Fox and Fox Searchlight are owned by News Corp.; Warner Bros. and New Line are units of Time Warner Inc.; MGM is owned by a group of former creditors including Highland Capital, Anchorage Advisors and Carl Icahn; Lionsgate is owned by Lions Gate Entertainment Corp.; IFC is owned by AMC Networks Inc.; Rogue is owned by Relativity Media LLC.

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EU drug regulator OKs Novartis' meningitis B shot

LONDON (AP) — Europe's top drug regulator has recommended approval for the first vaccine against meningitis B, made by Novartis AG.

There are five types of bacterial meningitis. While vaccines exist to protect against the other four, none has previously been licensed for type B meningitis. In Europe, type B is the most common, causing 3,000 to 5,000 cases every year.

Meningitis mainly affects infants and children. It kills about 8 percent of patients and leaves others with lifelong consequences such as brain damage.

In a statement on Friday, Andrin Oswald of Novartis said he is "proud of the major advance" the company has made in developing its vaccine Bexsero. It is aimed at children over two months of age, and Novartis is hoping countries will include the shot among the routine ones for childhood diseases such as measles.

Novartis said the immunization has had side effects such as fever and redness at the injection site.

Recommendations from the European Medicines Agency are usually adopted by the European Commission. Novartis also is seeking to test the vaccine in the U.S.

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Medics: Israel strike intended for militants kills 11 Gaza civilians

GAZA CITY, Gaza Strip (AP) — An Israeli missile flattened a two-story house in a residential neighborhood of Gaza City on Sunday, killing at least 11 civilians, mostly women and children, Palestinian medical officials said, as Israel expanded a military offensive to target homes of wanted militants.

The attack, which Israel said targeted a militant, was the single deadliest incident of the five-day-old Israeli operation and hiked a toll Sunday that was already the highest number of civilians killed in one day, according to Gaza medics. The bloodshed is likely to raise international pressure for a cease-fire, with Egypt taking the leading role in mediating between Israel and Hamas.

President Barack Obama said he had been in touch with the leaders of Israel, Egypt, and Turkey in an effort to halt the fighting. "We're going to have to see what kind of progress we can make in the next 24, 36, 48 hours," he said.

Obama cautioned against a potential Israeli ground invasion into Gaza, warning it could only deepen its death toll. At the same time, he blamed Palestinian militants for starting the round of fighting by raining rockets onto Israel, and he defended Israel's right to defend itself.

"Israel has every right to expect that it does not have missiles fired into its territory," Obama said in Thailand at the start of a three-nation tour in Asia.

An Israeli envoy arrived in Cairo on Sunday and held talks with Egyptian officials on a ceasefire, according to Egyptian security officials and Nabil Shaath, a top aide of Palestinian President Mahmoud Abbas who was in the Egyptian capital.

But Israel and Gaza's militant Hamas rulers remain far apart on any terms for a halt in the bloodshed, which has killed 70 Palestinians — including 36 civilians, according to Gaza health officials — and three Israeli civilians.

Hamas is linking a truce deal to a complete lifting of the border blockade on Gaza imposed since Islamists seized the territory by force. Hamas also seeks Israeli guarantees to halt targeted killings of its leaders and military commanders. Israeli officials reject such demands. They say they are not interested in a "timeout," and want firm guarantees that militant rocket fire into Israel will finally end. Past ceasefires have been short lived.

As the offensive moved forward, Israel found itself at a crossroads — on the cusp of launching a ground offensive into Gaza to strike an even tougher blow against Hamas, or pursuing Egyptian-led truce efforts.

"The Israeli military is prepared to significantly expand the operation," Israeli Prime Minister Benjamin Netanyahu declared at the start of the weekly Cabinet meeting.

At the same time, Gaza militants continued their barrage of rocket fire at Israel, firing more than 100, including two at Tel Aviv. More than 10 Israelis were injured by shrapnel, two moderately, according to police spokesman Mickey Rosenfeld. Israel's "Iron Dome" rocket-defense system shot down at least 30 rockets, including the ones aimed at Tel Aviv.

Israel's announcement Sunday that it was widening its campaign to target homes of militants appeared to mark a new and risky phase of the operation, given the likelihood of civilian casualties in the densely populated territory of 1.5 million Palestinians. Israel launched the offensive Wednesday in a bid to end months of intensifying rocket fire from the Hamas-ruled Gaza Strip.

The day's deadliest strike hit the home of the Daloo family in Gaza City, reducing the structure to rubble.

Frantic rescuers pulled the bodies of several children from the ruins of the house, including a toddler and a 5-year-old, as survivors and bystanders screamed in grief. Later, the bodies of the children were laid out in the morgue of Gaza City's Shifa Hospital.

Among the 11 dead were four small children and five women, including an 80-year-old, Gaza health official Ashraf al-Kidra said.

Israeli military spokesman Brig Gen. Yoav Mordechai told Channel 2 TV that the Israeli navy had targeted the building and killed a "global jihad" militant.

"The targets are exact," Mordechai said. "Every (Israeli) missile has an address."

He said the army would continue its operation "as if there were no (cease-fire) talks in Egypt."

The presence of a militant in the house could not be verified. Al-Kidra said the two adult men killed in the strike were civilians.

Sami Abu Zuhri, a Hamas spokesman, said that "the Israeli people will pay the price" for the killing of civilians. One of the rocket attacks targeting Tel Aviv came soon after the strike on the Daloo home.

More than a dozen homes of Hamas commanders or families linked to Hamas were struck on Sunday. Though most were empty — their inhabitants having fled to shelter — at least three still had families in them. Al-Kidra said 19 of the 24 people killed Sunday were civilians, mostly women and children.

Israeli Vice Premier Moshe Yaalon said civilian casualties are inevitable.

"You can't avoid collateral damage if they position the rockets in densely populated areas, in mosques, school yards. We shouldn't be blamed for the outcome," he said.

Israel also struck two high-rise buildings housing media outlets, damaging the top floor offices of the Hamas TV station, Al Aqsa, and a Lebanese-based broadcaster, Al Quds TV, seen as sympathetic to the Islamists. Six Palestinian journalists were wounded, including one who lost a leg, a Gaza press association said.

Foreign broadcasters, including British, German and Italian TV outlets, also had offices in the high-rises.

Two missiles made a direct hit on Al Aqsa TV's 15th floor offices, said Bassem Madhoun, an employee of Dubai TV, which has offices in the same building.

Building windows were blown out and glass shards and debris were scattered on the street below. Some of the journalists who had been inside the building at the time took cover in the entrance hallway.

Lt. Col. Avital Leibovich, an Israeli military spokeswoman, said the strikes targeted Hamas communications equipment on the buildings' rooftops. She accused the group of using journalists as "human shields," and urged journalists to stay clear of Hamas bases and facilities.

The repeated militant rocket fire on Tel Aviv and a volley fired Friday toward Jerusalem have significantly escalated the hostilities by widening the militants' rocket range and putting 3.5 million Israelis, or half the country's population, within reach. The attempt to strike Jerusalem also has symbolic resonance because both Israel and the Palestinians claim the holy city for a capital.

Israeli radio stations repeatedly interrupted their broadcasts to air "Code Red" alerts warning of impending rocket strikes. In the southern city of Ashkelon, rocket fire damaged a residential building, punching a hole in the ceiling and riddling the facade with shrapnel.

With fighting showing no signs of slowing, international attempts to broker a ceasefire continued.

Nabil Shaath, an aide to Palestinian President Mahmoud Abbas who was in Cairo, confirmed that the Israeli envoy had arrived in Egypt for talks, saying there are "serious attempts to reach a ceasefire." There was no immediate Israeli confirmation.

Hamas' prime minister, Ismail Haniyeh, spoke to Egyptian President Mohammed Morsi. He told the Egyptian leader he supports such efforts, provided Hamas receives "guarantees that will prevent any future aggression" by Israel, his office said in a statement.

Morsi over the weekend hosted talks with Hamas' supreme leader, as well as leaders from Hamas allies Turkey and Qatar. He also held contacts with Western leaders.

French Foreign Minister Laurent Fabius visited Israel on Sunday to offer his country's help toward forging an "immediate ceasefire," the French government said.

Meeting with Fabius, Israeli Foreign Minister Avigdor Lieberman thanked him for "France's efforts to prevent casualties" but said "the moment that all the terror organizations announce a ceasefire, we can consider all the ideas that French foreign minister and other friends are raising."

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Aron Heller contributed reporting from Beersheba.

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